Bradley Maron

Dr. Maron is an Assistant Professor of Medicine at Harvard Medical School, Associate Physician in the Division of Cardiovascular Medicine at Brigham and Women’s Hospital, and Co-director of the Pulmonary Vascular Disease Center at the VA Boston Healthcare System. His laboratory focus involves utilizing network medicine and systems biology to characterize the pathobiological mechanisms underpinning complex cardiovascular disease. Through these approaches, Dr. Maron identified a critical cysteinyl thiol redox switch as well as a pro-thrombotic peptide in the CAS protein NEDD9 that regulates pulmonary vascular fibrosis and thrombosis, respectively. These molecular targets have emerged as potentially modifiable small molecule and antibody technologies. In collaborative work, he led international projects focusing on the hemodynamic spectrum of clinical risk in pulmonary hypertension, which has provided new insights on pulmonary artery pressure and pulmonary vascular resistance levels that are associated with adverse clinical outcomes. More recently, he has applied network medicine to individualizing the pathobiology of patients with hypertrophic cardiomyopathy. Dr. Maron has co-authored numerous scientific manuscripts, is the co-inventor of several patents or pending patents and is funded by the National Institutes of Health, American Heart Association, and many other Foundations. He is a member of the American Society of Clinical Investigation, a recipient of the distinguished Eleanor and Miles Shore Scholar in Medicine fellowship, a McKenzie Family Master Clinician, and a recipient of Harvard Medical School’s Excellence in Teaching Awards.