Ubiquigent Ltd
Sheelagh Frame is the Chief Scientific Officer and Head of Biology at Ubiquigent Ltd. Sheelagh previously worked at Cyclacel Limited as a Program Manager in Oncology & Autoimmune/Inflammation. Prior to that, Sheelagh was a Senior Postdoctoral Fellow at the University of Dundee and a Postdoctoral Research Scientist at Onyx Pharmaceuticals, Inc. Sheelagh holds a PhD in Medicine from the University of Glasgow and a BSc Hons in Molecular Biology from The University of Edinburgh.
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Ubiquigent Ltd
Ubiquigent enables the discovery and development of novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need. Founded 13 years ago, the Company has an unrivalled track record and unique range of specialist services focused on the exploitation of the DUB enzymes and ubiquitin-proteasome system (UPS). As the partner chosen by many leading industry and academic organisations for their drug discovery programmes, Ubiquigent’s experience spans the development of DUB inhibitors and modulators in the fields of protein degradation, stabilisation, and homeostasis. Ubiquigent has an internal pipeline of drug discovery programmes and is developing a strong IP portfolio encompassing DUB inhibitors, DUB-targeting Proteolysis Targeting Chimeras (PROTACs) and DUB-Targeting Chimeras (DUBTACs) for partnering and commercialisation.