vishwanath K chandrahas

Senior Scientist II at B2S Life Sciences

Vishwanath K Chandrahas has extensive experience in the field of life sciences, spanning over 16 years. vishwanath K currently holds the position of Senior Scientist II at B2S Life Sciences, where they specialize in biophysical and biochemical characterization of proteins/antibodies. This involves conducting detailed binding kinetics of Antigen-Antibody/Ligand-Receptor pairs using advanced systems like Octet-HTX and Red96 of BLI.

Prior to their current role, Vishwanath served as a Postdoctoral Researcher at the University of Wisconsin-Madison from 2018 to 2021. During this time, they independently led laboratory research focused on exploring the role of IQGAP scaffold proteins in Epidermal Growth Factor Receptor (EGFR) mediated activation of the PI3 Kinase/Akt signaling pathway and autophagy. Their work also uncovered a novel link between IQGAP3-EGF Receptor-Autophagy pathways, revealing the regulatory role of IQGAP3 in autophagy.

From 2015 to 2018, Vishwanath worked as a Scientific Researcher at the Sanford Burnham Prebys Medical Discovery Institute. Here, they investigated the role of inositol tri-phosphate receptors (IP3R) in the generation of reactive oxygen species (ROS) during unfolded protein response (UPR). Their research highlighted the up-regulation of IP3R expression under UPR-induced ER stress, suggesting a connection between ER stress and calcium signaling.

Vishwanath's academic journey began as a PhD student at the University of Notre Dame in 2008, where they focused on studying protein-protein interactions to understand the functional significance of streptococcal proteins binding to human plasminogen. Their research elucidated the critical role of direct binding between streptococcal PAM and human plasminogen in the virulence of Group A Streptococcus.

Before pursuing their PhD, Vishwanath served as a Protein Purification Expert at the National Center for Biological Sciences from 2005 to 2008. In this role, they gained expertise in protein purification techniques.

Overall, Vishwanath K Chandrahas has made significant contributions to the field of life sciences through their research and expertise in protein characterization, receptor signaling pathways, and protein-protein interactions.

Vishwanath K Chandrahas pursued their Bachelor's degree in Agriculture, General from the University of Agricultural Sciences, Bangalore, from 1999 to 2003. vishwanath K then went on to complete their Master's degree in Biotechnology from the same university, from 2003 to 2005. Later, Vishwanath attended the University of Notre Dame from 2008 to 2012, where they earned their Doctor of Philosophy (PhD) in Biochemistry.

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