Bill Brubaker

Senior Vice President of Nonclinical Development, Head of Pharmacokinetics and Drug Metabolism at Engrail Therapeutics

Bill Brubaker has a diverse and extensive work experience in the pharmaceutical industry. Bill is currently working as the Senior Vice President of Nonclinical Development and Head of Pharmacokinetics and Drug Metabolism at Engrail Therapeutics since January 2023. Prior to this, they served as the Vice President of Nonclinical Development and Head of Pharmacokinetics and Drug Metabolism at the same company from February 2022 to January 2023.

Before joining Engrail Therapeutics, Bill Brubaker founded and served as the President of Farmington Pharma since November 2003. At Farmington Pharma, they provided preclinical development consulting and conducted in vivo pharmacokinetic contract lab studies for biotechs, pharma, and VC firms.

Bill Brubaker has also worked as a Project Lead/Senior Consultant at Ultragenyx Pharmaceutical Inc. from April 2015 to May 2018. Bill served as the Chief Executive Officer of Bikam Pharmaceuticals, Inc. from September 2012 to 2014 and successfully led the company to its acquisition by Shire Pharmaceuticals. Bikam Pharmaceuticals focused on developing disease-altering small molecule pharmacological chaperones for the treatment of retinal diseases.

In addition, Bill Brubaker worked as the Senior Director of Orphan and Genetic Diseases at Pfizer Pharmaceuticals from August 2010 to August 2012. Bill also held the position of VP of Preclinical Development at Achillion Pharmaceuticals from 2004 to 2009.

Earlier in their career, Bill Brubaker served as the Executive Director of Preclinical Development at MEMORY Pharmaceuticals from 2000 to 2003. Bill played a crucial role in building the preclinical development infrastructure and strategy for translational research. Before that, they worked as the Director of Preclinical Drug Metabolism at Bayer Pharmaceuticals from 1990 to 2000.

Overall, Bill Brubaker has demonstrated expertise and leadership in nonclinical development, pharmacokinetics, and preclinical development throughout their career.

Bill Brubaker received their B.S. in Chemistry from East Stroudsburg University of Pennsylvania in 1977. After that, they pursued their Ph.D. in Chemistry at Virginia Tech, which they completed between 1977 and 1982. Following their Ph.D., Brubaker went on to pursue a Post-Doctoral Fellowship in Pharmacology/Medicinal Chemistry at Yale University School of Medicine from 1983 to 1985. It is unknown when they attended Central Dauphin East or if they obtained any degree or field of study from there.

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