Vp, Head Of Metabolic Disease Biology

Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company has completed an initial public offering (IPO) in February of 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.

Position Summary

This role will be the Head of Metabolic Disease Biology, provide scientific leadership to metabolic disease biology and discovery pipeline, and closely work with the Head of Biology to contribute to the overall company discovery portfolio strategy. This role will build and lead Metabolic Disease Biology team, recruit talents, and use their experience and skills to lead preclinical programs for metabolic diseases. This role will closely collaborate with cross-functional teams to drive discovery programs.   

Essential Duties and responsibilities

• Provide scientific leadership to metabolic disease biology and discovery pipeline.
• Identify possible therapeutic targets, contribute to metabolic disease portfolio strategy, and work with multifunctional teams for the execution of that strategy.
• Lead biology for discovery programs for metabolic disease pipeline. Drive pipeline progress and achieve milestones.
• Lead the efforts to establish assays and/or animal models to validate targets and to discover therapeutics. Oversee the design and execution of in vitro/in vivo studies in disease models either on an internal basis or with external partners.
• Interpret and analyze data as well as present progress to internal stakeholders and external collaborators.
• Develop and lead the metabolic disease biology team. Recruit talents. Lead, mentor, and train team members.
• Ensure high scientific standard and high-quality research.
• Ensure efficient collaboration with cross-functional project teams, effective communication, and stakeholder management.

QUALIFICATIONS: 

• PhD in Biology or related field with at least 10 years of post-doctoral experience and 5+ years in industry
• Deep knowledge in metabolic disease biology and MOA of the diseases
• Experience in in vitro and animal models for metabolic diseases.
• Experience with directing programs from discovery to IND
• Previous experience with people management is required.
• Excellent organizational, written and oral communication skills, strong leadership and collaboration skills, efficient time management, and high degree of flexibility.