Tessera Therapeutics
- Senior Research Associate/associate Scientist, Bioanalytical
Senior Research Associate/associate Scientist, Bioanalytical
MA, United States
Job description
Company Summary:
Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.
Position Summary:
We are seeking a highly motivated and collaborative researcher to join our DMPK group at Tessera Therapeutics. This position reports to the Associate Director of DMPK, and will offer an exciting opportunity to develop and employ LC-MS methods to quantitate oligonucleotides to support research, non-clinical, and clinical development programs for a variety of therapeutic indications. We are searching for a driven, enthusiastic, and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform.
Job Responsibilities
- Prepare and extract oligonucleotides from various biological matrices including biofluids, tissues, cells, and subcellular fractions, ensuring high-quality results.
- Design and execute experiments from sample preparation, LC-MS/MS operation to data analysis.
- Contribute to LC-MS method development for quantitation of oligonucleotides in various biological matrices.
- Follow method SOPs for sample analysis and data collection.
- Clearly document and maintain laboratory notebooks and computer documentation.
- Collaborate with cross-functional teams to provide bioanalytical support.
- Work in accordance with health and safety guidelines and company policies.
- Other duties as assigned.
- Bachelor's degree with 5+ years of related industry, or Master's degree with 3+ years of related industry experience.
- Hands-on experience operating and maintaining an LC-MS system and running high throughput bioanalytical analysis are required.
- Knowledge of biological sample preparation and extraction techniques for downstream LC-MS analysis.
- Excellent organizational and communication skills.
- Ability to conduct multiple laboratory and project tasks efficiently.
- Ability to work in a team-oriented environment with flexibility.
- Good attention to details and a good ability to maintain precise records are essential.
Preferred Qualifications:
- Hands-on experience in RNA extraction from in vivo samples such as blood or tissue is a plus.
- Experience in automated liquid handling instruments, such as Hamilton and KingFisher, is a plus.
- Experience in biotech or pharma industry is preferred.
More about Tessera Therapeutics:
Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or Accommodations@tesseratx.com
Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.
Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.
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